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Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome2071 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1482 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1370 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1310 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1287 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1242 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1158 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1080 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1064 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1014 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome980 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome967 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome947 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome889 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome885 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome879 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome860 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome857 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome800 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome781 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome744 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Autoimmune Retinopathy664 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy637 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy612 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy593 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy586 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy568 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy565 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy563 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy555 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy543 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy541 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy539 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy538 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy535 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy531 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy530 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy527 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy523 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy521 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy519 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy513 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy509 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy507 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy506 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy504 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy501 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy500 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy494 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy493 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy491 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy490 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy489 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy488 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy482 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy481 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy481 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Multifocal Vitelliform Macular Dystrophy480 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Multifocal Vitelliform Macular Dystrophy478 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy476 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy476 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Multifocal Vitelliform Macular Dystrophy475 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy473 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy472 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy471 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy469 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy468 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy467 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy463 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy463 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Multifocal Vitelliform Macular Dystrophy462 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy460 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy459 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy456 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy452 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy450 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy450 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy449 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy446 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Multifocal Vitelliform Macular Dystrophy437 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy436 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy424 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Multifocal Vitelliform Macular Dystrophy421 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Multifocal Vitelliform Macular Dystrophy415 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Bilateral Diffuse Melanocytic Proliferation (BDUMP)391 views67 year old man
Vision is better after 14 plasma exchanges, OD 20/160, OS 20/32

Bilateral Diffuse Melanocytic Proliferation (BDUMP)362 views67 year old man
The patient started noticing dimming of the vision in November of 2020.Â He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.Â The vision did not improve with the cataract surgery.Â On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.Â The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.Â He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.Â Â A retinal evaluation showed subretinal fluid and vision loss. Â The peripheral vision and central vision were pretty good.Â The vision did seem to get better off the nivolumab.Â Then when the patient returned to Florida in September and now the vision is getting worse.Â The patient did not have any treatments in either eye.Â The patient is now off the oncology treatment.Â He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.Â It was stopped because of a skin rash and reactions.Â Â
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.

Bilateral Diffuse Melanocytic Proliferation (BDUMP)361 views67 year old man
The patient started noticing dimming of the vision in November of 2020.Â He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.Â The vision did not improve with the cataract surgery.Â On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.Â The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.Â He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.Â Â A retinal evaluation showed subretinal fluid and vision loss. Â The peripheral vision and central vision were pretty good.Â The vision did seem to get better off the nivolumab.Â Then when the patient returned to Florida in September and now the vision is getting worse.Â The patient did not have any treatments in either eye.Â The patient is now off the oncology treatment.Â He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.Â It was stopped because of a skin rash and reactions.Â Â
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.

Bilateral Diffuse Melanocytic Proliferation (BDUMP)360 views67 year old man
Vision is better after 14 plasma exchanges, OD 20/160, OS 20/32

Bilateral Diffuse Melanocytic Proliferation (BDUMP)357 views67 year old man
The patient started noticing dimming of the vision in November of 2020.Â He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.Â The vision did not improve with the cataract surgery.Â On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.Â The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.Â He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.Â Â A retinal evaluation showed subretinal fluid and vision loss. Â The peripheral vision and central vision were pretty good.Â The vision did seem to get better off the nivolumab.Â Then when the patient returned to Florida in September and now the vision is getting worse.Â The patient did not have any treatments in either eye.Â The patient is now off the oncology treatment.Â He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.Â It was stopped because of a skin rash and reactions.Â Â
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.

Bilateral Diffuse Melanocytic Proliferation (BDUMP)355 views67 year old man
The patient started noticing dimming of the vision in November of 2020.Â He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.Â The vision did not improve with the cataract surgery.Â On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.Â The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.Â He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.Â Â A retinal evaluation showed subretinal fluid and vision loss. Â The peripheral vision and central vision were pretty good.Â The vision did seem to get better off the nivolumab.Â Then when the patient returned to Florida in September and now the vision is getting worse.Â The patient did not have any treatments in either eye.Â The patient is now off the oncology treatment.Â He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.Â It was stopped because of a skin rash and reactions.Â Â
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.

Bilateral Diffuse Melanocytic Proliferation (BDUMP)351 views67 year old man
The patient started noticing dimming of the vision in November of 2020.Â He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.Â The vision did not improve with the cataract surgery.Â On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.Â The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.Â He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.Â Â A retinal evaluation showed subretinal fluid and vision loss. Â The peripheral vision and central vision were pretty good.Â The vision did seem to get better off the nivolumab.Â Then when the patient returned to Florida in September and now the vision is getting worse.Â The patient did not have any treatments in either eye.Â The patient is now off the oncology treatment.Â He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.Â It was stopped because of a skin rash and reactions.Â Â
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.

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