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Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome2087 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1491 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1381 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1324 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1304 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1253 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1171 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1091 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1076 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome1028 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome995 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome982 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome962 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome897 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome896 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome888 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome871 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome813 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome795 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Bilateral Diffuse Uveal Melanocytic Proliferation - BDUMP - Paraneoplastic Syndrome753 views80-year-old man vision loss for one year. He died about one year after these photos from Metastatic Poorly Differentiated Large Cell Carcinoma of unknown primary. He was a smoker.

Autoimmune Retinopathy678 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy648 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy622 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy608 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy595 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy580 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy577 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy574 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy563 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy553 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy550 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy549 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy548 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy545 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy542 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy540 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy539 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy538 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy536 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy535 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy531 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy529 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy524 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy523 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy520 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy520 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Multifocal Vitelliform Macular Dystrophy517 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy513 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy512 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy511 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy509 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy505 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy503 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy500 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy499 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy498 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy493 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy492 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy492 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Multifocal Vitelliform Macular Dystrophy488 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy487 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy487 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Multifocal Vitelliform Macular Dystrophy486 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Multifocal Vitelliform Macular Dystrophy485 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy483 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy482 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy482 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy479 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy478 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy477 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy475 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy475 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Multifocal Vitelliform Macular Dystrophy473 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy470 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy468 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy467 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy465 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Autoimmune Retinopathy463 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy461 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy460 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy460 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Multifocal Vitelliform Macular Dystrophy459 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy458 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy445 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Autoimmune Retinopathy443 views91 year old female with severe vision loss over the past 3 years. She has shimmery scotomas. The main findings are outer retinal atrophy evident on OCT and FAF. VA 20/80 OD and 20/125 OS

Multifocal Vitelliform Macular Dystrophy435 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Multifocal Vitelliform Macular Dystrophy434 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Multifocal Vitelliform Macular Dystrophy424 views58 year old female with mild vision loss - 20/20 OU - extensive testing has shown no cancer. Case of Karina Findlay, MD

Bilateral Diffuse Melanocytic Proliferation (BDUMP)401 views67 year old man
Vision is better after 14 plasma exchanges, OD 20/160, OS 20/32

Bilateral Diffuse Melanocytic Proliferation (BDUMP)375 views67 year old man
The patient started noticing dimming of the vision in November of 2020.Â He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.Â The vision did not improve with the cataract surgery.Â On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.Â The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.Â He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.Â Â A retinal evaluation showed subretinal fluid and vision loss. Â The peripheral vision and central vision were pretty good.Â The vision did seem to get better off the nivolumab.Â Then when the patient returned to Florida in September and now the vision is getting worse.Â The patient did not have any treatments in either eye.Â The patient is now off the oncology treatment.Â He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.Â It was stopped because of a skin rash and reactions.Â Â
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.

Bilateral Diffuse Melanocytic Proliferation (BDUMP)372 views67 year old man
The patient started noticing dimming of the vision in November of 2020.Â He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.Â The vision did not improve with the cataract surgery.Â On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.Â The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.Â He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.Â Â A retinal evaluation showed subretinal fluid and vision loss. Â The peripheral vision and central vision were pretty good.Â The vision did seem to get better off the nivolumab.Â Then when the patient returned to Florida in September and now the vision is getting worse.Â The patient did not have any treatments in either eye.Â The patient is now off the oncology treatment.Â He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.Â It was stopped because of a skin rash and reactions.Â Â
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.

Bilateral Diffuse Melanocytic Proliferation (BDUMP)370 views67 year old man
Vision is better after 14 plasma exchanges, OD 20/160, OS 20/32

Bilateral Diffuse Melanocytic Proliferation (BDUMP)366 views67 year old man
The patient started noticing dimming of the vision in November of 2020.Â He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.Â The vision did not improve with the cataract surgery.Â On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.Â The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.Â He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.Â Â A retinal evaluation showed subretinal fluid and vision loss. Â The peripheral vision and central vision were pretty good.Â The vision did seem to get better off the nivolumab.Â Then when the patient returned to Florida in September and now the vision is getting worse.Â The patient did not have any treatments in either eye.Â The patient is now off the oncology treatment.Â He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.Â It was stopped because of a skin rash and reactions.Â Â
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.

Bilateral Diffuse Melanocytic Proliferation (BDUMP)364 views67 year old man
The patient started noticing dimming of the vision in November of 2020.Â He had rapidly worsening cataracts. He had the cataract surgery done in both eyes in April of 2021.Â The vision did not improve with the cataract surgery.Â On June 1 of 2021 he had immunotherapy for his renal cell carcinoma and then developed severe vision loss.Â The patient noticed that one of the commercials for nivolumab (checkpoint inhibitor targeting programmed death receptor-1) said it may cause vision loss.Â He recalled that he started the nivolumab in October of 2020 and had vision loss starting then.Â Â A retinal evaluation showed subretinal fluid and vision loss. Â The peripheral vision and central vision were pretty good.Â The vision did seem to get better off the nivolumab.Â Then when the patient returned to Florida in September and now the vision is getting worse.Â The patient did not have any treatments in either eye.Â The patient is now off the oncology treatment.Â He was then started on a TKI cabometex for the cancer which was dosed in mid June through mid July just for a month.Â It was stopped because of a skin rash and reactions.Â Â
VA OD: Dcc20/200-2 PHNI Ncc20/800
VA OS: Dcc20/63 PHNI NccJ7 He has been off the checkpoint inhibitor for a year.

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